KMID : 0387719930040010103
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Korean Journal of Blood Transfusion 1993 Volume.4 No. 1 p.103 ~ p.107
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ABO Discrepancy due to Cis-A2B3
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ÇÏ°æÀÓ
Àüâȣ/±è¿ìÅÃ/Â÷ÀÀ³²/°¼®/¿À¿µÃ¶
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Abstract
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An unusual blood group inheritance, that is, a phenotype 0 child who was born from AB¡¿A1 parents is reported.
It has been known that cis-AB occurs by the unequal chromosomal crossing-over producing a single chromosome with the genes for A and B enzymes or the structural mutation in A or B genes producing a single abnormal emzyme with the bifunctional
activity
associated with blood group substances. Cis-AB may provide discrepancy between cell and serum typing in ABO blood groups, and make problems in parternity and transfusion.
Recently, authors experienced the cis-A2B3 with 0 child, so we reported with brief review of literatures.
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KEYWORD
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